SMFM Consult Series #44, Management of bleeding in the late preterm period

Third-trimester bleeding is a common complication arising from a variety of etiologies, some of which may initially present in the late preterm period. Previous management recommendations have not been specific to this gestational age window, which carries a potentially lower threshold for delivery. The purpose of this document is to provide guidance on management of late preterm (34 0/7-36 6/7weeks of gestation) vaginal bleeding. The following are Society for Maternal-Fetal Medicine recommendations:(1) we recommend delivery at 36-37 6/7 weeks of gestation for stable women with placenta previa without bleeding or other obstetric complications (GRADE 1B); (2) we do not recommend routine cervical length screening for women with placenta previa in the late preterm period due to a lack of data on an appropriate management strategy (GRADE 2C); (3) we recommend delivery between 34 and 37 weeks of gestation for stable women with placenta accreta (GRADE 1B);(4) we recommend delivery between 34 and 37 weeks of gestation for stable women with vasa previa(GRADE 1B); (5) we recommend that in women with active hemorrhage in the late preterm period,delivery should not be delayed for the purpose of administering antenatal corticosteroids (GRADE 1B);(6) we recommend that fetal lung maturity testing should not be used to guide management in the late preterm period when an indication for delivery is present (GRADE 1B); and (7) we recommend that antenatal corticosteroids should be administered to women who are eligible and are managed expectantly if delivery is likely within 7 days, the gestational age is between 34 0/7 and 36 6/7 weeks of gestation, and antenatal corticosteroids have not previously been administered (GRADE 1A).

Last Reaffirmed: Aug 1, 2022